Tyson & HolyfieldCHICAGO — Boxing rivals Mike Tyson and Evander Holyfield are to meet again — and this time Oprah will referee.

Harpo Productions announced Wednesday the two fighters would appear on Friday’s live episode of “The Oprah Winfrey Show” from Chicago.

On June 28, 1997, at the MGM Grand in Las Vegas, Tyson was disqualified after biting off part of Holyfield’s right ear during their WBA heavyweight title fight.

Winfrey aired an interview with Tyson on Monday during which he discussed the death of his 4-year-old daughter and talked about his family. Harpo Productions says Tyson will take questions from the audience on Friday.